Decreased platelet 3H-imipramine binding sites in classical migraine.

نویسندگان

  • D P Geaney
  • M G Rutterford
  • J M Elliott
  • M Schächter
  • K M Peet
  • D G Grahame-Smith
چکیده

Patients with classical migraine investigated between attacks had significantly fewer platelet 3H-imipramine binding sites than control subjects and this finding was more marked in males than in females. There was no abnormality of binding characteristics of platelet 5-hydroxytryptamine receptors or of platelet alpha 2-adrenoceptors. Because the reduced 3H-imipramine binding capacity was found in classical migraineurs who were investigated between attacks, it may reflect a predisposition to migraine rather than being a consequence of attacks.

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عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره 47 7  شماره 

صفحات  -

تاریخ انتشار 1984